Before modern medicine and before vaccinations, smallpox was a feared disease that killed a third of its victims and crippled many of the survivors. At some point it was discovered that if nasal cotton swabs or other bodily fluids from an infected person was introduced as a powder through the nostrils or pressed against a small open wound, the procedure would ideally provoke a mild form of the illness, with reduced mortality from >30% to typically <2%, and subsequent immunity.

In the case of SARS-CoV-2 the severity of the illness seems to be liked to the entry vector, which made me think that inoculation, or variolation, could be a way to induce mild COVID-19 disease, and as a bonus give the patient immunity. So I’m now looking for an actual expert that can tell me that it won’t work and that the idea is totally fruitless, if not outright dangerous.

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